Avoid delivering therapies for non-sustained arrhythmias in ICD patients

Although implantable cardioverter-defibrillators (ICDs)/cardiac resynchronization therapy-defibrillators (CRT-Ds) have a significant role in preventing sudden cardiac death (SCD) in high-risk patients, especially for secondary prevention, inappropriate ICD shocks are common (8-40%). They are associated with high morbidity as well.
Hypothesis:
Programming ICDs to increased detection intervals before therapy administration would be safe and efficacious as compared with conventional programming.
Patients undergoing ICD implantation were randomized in a 1:1 fashion to either prolonged detection (30 of 40 intervals) or routine programming (18 of 24 intervals). All ICDs were programmed to detect arrhythmias with a cycle length of ≤320 msec. A